Search Results
13 results for search term 'Epithelium' in category Model System
human kidney organoid with Ai9 (tdTomato) fluorescence-on reporterModel System - [In Vitro] [Collaborative Opportunity Fund] [Human]Show Experiments (1) |
BALB/c mouseModel System - [In Vivo] [Delivery Systems Initiative] [Mouse]Show Experiments (1)
Testing Shuttle Peptides ability to deliver GFP-NLS to airway epithelia.
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mTmG mouseModel System - [In Vivo] [Delivery Systems Initiative] [Mouse] |
Ai9 mouse (BCM)Model System - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] |
Ai9 mouseModel System - [In Vivo] [Small Animal Testing Center (SATC), AAV tropism, Delivery Systems Initiative] [Mouse]Show Experiments (11)
Testing gRNA sequence and gRNA scaffold modified in Ai9 mice.
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Ai9-SauSpyCas9 mouseModel System - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] |
Macaca mulatta (Rhesus Macaque)Model System - [In Vivo] [Collaborative Opportunity Fund] [Rhesus macaque]Show Experiments (1)
Amphiphilic Peptides Deliver Base Editor RNPs to Rhesus Monkey Airway
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mTmG mouse (congenic)Model System - [In Vivo] [Small Animal Testing Center (SATC), Delivery Systems Initiative] [Mouse]Show Experiments (7)
Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA using the S10 shuttle peptide to activate the mTmG reporter in mouse brain
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C57BL/6J mouseModel System - [In Vivo] [Delivery Systems Initiative] [Mouse]Show Experiments (3)
Testing new LNPs (lipid nanoparticles) for delivery of Fluc mRNA in adult mice
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C57BL/6 mouse (Asokan study)Model System - [In Vivo] [Delivery Systems Initiative] [Mouse] |
Ai14 mouse (congenic)Model System - [In Vivo] [Small Animal Testing Center (SATC), Delivery Systems Initiative] [Mouse]Show Experiments (4)
Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in adult mouse cochlea
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Ai14 mouseModel System - [In Vivo] [Delivery Systems Initiative] [Mouse] |
13 results for search term 'Epithelium' in category Model System
Type | Organism | Subtype | Name | Description | Source | View Associated.. |
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Organoid | Human | human kidney organoid with Ai9 (tdTomato) fluorescence-on reporter | Kidney organoids were derived from a human iPS cell line with Ai9 (tdTomato) fluorescence-on reporter knocked into the AAVS1 safe harbor locus. | Beno Freedman Lab |
Show Experiments (1) |
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Animal | Mouse | BALB/c mouse | BALB/cJ is a commonly used inbred. Key traits include a susceptibility to developing the demyelinating disease upon infection with Theiler's murine encephalomyelitis virus. The BALB/cJ substrain is susceptible to Listeria, all species of Leishmania, and several species of Trypanosoma, but is resistant to experimental allergic orchitis (EAO). | The Jackson Laboratory |
Show Experiments (1)
Testing Shuttle Peptides ability to deliver GFP-NLS to airway epithelia.
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Animal | Mouse | mTmG mouse | ROSAmT/mGÂ is a cell membrane-targeted, two-color fluorescent Cre-reporter allele. Prior to Cre recombination, cell membrane-localized tdTomato (mT) fluorescence expression is widespread in cells/tissues. Cre recombinase expressing cells (and future cell lineages derived from these cells) have cell membrane-localized EGFP (mG) fluorescence expression replacing the red fluorescence | The Jackson Laboratory | ||
Animal | Mouse | Ai9 mouse (BCM) | Ai9 mouse has a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven red fluorescent protein variant (tdTomato) - all inserted into the Gt(ROSA)26Sor locus. | Baylor College of Medicine | ||
Animal | Mouse | Ai9 mouse | Ai9 mouse has a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven red fluorescent protein variant (tdTomato) - all inserted into the Gt(ROSA)26Sor locus. | The Jackson Laboratory |
Show Experiments (11)
Testing gRNA sequence and gRNA scaffold modified in Ai9 mice.
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Animal | Mouse | Ai9-SauSpyCas9 mouse | Ai9-SauSpyCas9 is a version of Ai9 that has a single guide RNA sites on both sides of the STOP cassette. This is a Cre reporter allele that has a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven red fluorescent protein variant (tdTomato) - all inserted into the Gt(ROSA)26Sor locus. Ai9 mice express robust tdTomato fluorescence following Cre-mediated recombination. | Baylor College of Medicine | ||
Animal | Rhesus macaque | Macaca mulatta (Rhesus Macaque) | Tarantal Lab |
Show Experiments (1)
Amphiphilic Peptides Deliver Base Editor RNPs to Rhesus Monkey Airway
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Animal | Mouse | mTmG mouse (congenic) | mTmG is a double-fluorescent reporter transgenic mouse which expresses membrane-targeted tdTomato flanked by loxP sequences, followed by membrane-targeted GFP. After genomic cleavage by Cas9 at two sites, or Cre recombinase between loxP sites, tdTomato expression is lost and GFP is expressed. | The Jackson Laboratory |
Show Experiments (7)
Delivery of unmodified, phosphorothioate (PS)-stabilized crRNA with chemically modified, PS-stabilized tracrRNA using the S10 shuttle peptide to activate the mTmG reporter in mouse brain
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Animal | Mouse | C57BL/6J mouse | C57BL/6J WT mouse | The Jackson Laboratory |
Show Experiments (3)
Testing new LNPs (lipid nanoparticles) for delivery of Fluc mRNA in adult mice
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Animal | Mouse | C57BL/6 mouse (Asokan study) | Unspecified | |||
Animal | Mouse | Ai14 mouse (congenic) | Ai14 mouse has a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven red fluorescent protein variant (tdTomato) - all inserted into the Gt(ROSA)26Sor locus. The att site flanked neo selection cassette has been removed in this strain. | The Jackson Laboratory |
Show Experiments (4)
Testing new LNPs (lipid nanoparticles) for delivery of Cas9 mRNA/sgRNA in adult mouse cochlea
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Animal | Mouse | B6 | C57BL/6J WT mouse | Baylor College of Medicine | ||
Animal | Mouse | Ai14 mouse | Ai14 mouse has a loxP-flanked STOP cassette preventing transcription of a CAG promoter-driven red fluorescent protein variant (tdTomato) - all inserted into the Gt(ROSA)26Sor locus. The att site flanked neo selection cassette has been removed in this strain. | The Jackson Laboratory |